Peptide Active Data Details
Basic Peptide Information
DICL ID
DICL_Pep_04568
Ion Channel
Small conductance calcium-activated potassium channel protein 1
Peptide Function
Blocker
Gene Name
KCNN1
Activity Data (nM)
IC50
8 nM
Ki
Not available
EC50
Not available
Kd
Not available
Biologically Active
Not specified
Sequence Information
Peptide Sequence
CNCKAPETALCARRCQQH
Peptide UniProt Accession
UniParc
UPI0000035420
Peptide Synonyms/Alias
[Apamin; 24345-16-2; Apamine; UNII-X644P85KUR; EINECS 246-182-7; C79H131N31O24S4; Ro 23-6721; X644P85KUR; Apamin (reduced) cyclic (1-11);(3-15)-bis(disulfide); DTXSID70897227; HB1051; MFCD00167944; AKOS024456726; L-Histidinamide; L-cysteinyl-L-asparaginyl-L-cysteinyl-L-lysyl-L-alanyl-L-prolyl-L-alpha-glutamyl-L-threonyl-L-alanyl-L-leucyl-L-cysteinyl-L-alanyl-L-arginyl-L-arginyl-L-cysteinyl-L-glutaminyl-L-glutaminyl-; cyclic (1-11)(3-15)-bis(disulfide); Apamin; Bee Venom - CAS 24345-16-2; NS00075519; Q417260]
Peptide Species
Apis mellifera (Honeybee)
Peptide Name
Apamin
CAS Number
24345-16-2
Experimental Conditions
pH
pH 7.4
Holding Potential (mV)
−110 mV
Temperature
21−23 °C
Test Method
Patch-clamping
Test Species
CHO cell (Chinese hamster ovary cell)
Binding Information
Binding Site
Not specified
Binding Site Residue
Not specified
Ion Channel Information
Gene Abbreviation (ABB)
KCa
Ion Channel UniProt Accession
Source Organism
Homo sapiens (Human)
References & Disease Information
Disease
Not specified
PubChem CID
URL
Not available
PMID
Patent
Not available